Ovagen - Synthesized Liver Peptide
Ovagen is a dietary supplement with а synthesized liver peptide. It normalizes the function of the liver by reducing its peptide deficiency and restoring protein synthesis inside its cells.
Ovagen is recommended for everyone whose liver may be compromised, especially elderly people and those with metabolic disorders, skin diseases, hepatitis, intoxication, liver failure, biliary dyskinesia, cirrhosis or complications from radiotherapy, chemotherapy or long-term antibiotic therapy.
Ovagen can be easily combined with other supplements and medicines and should be used in addition to conventional medical treatments.
Biologically active food supplement Ovagen is a peptide complex containing the following amino acids: glutamine, asparagine and leucine, which normalize the functions of liver cells.
Ovagen is manufactured in the form of tablets or capsules, each containing 0.100 mg of an active substance.
Experimental studies in the liver organotypic tissue culture have shown, that the peptide complex is capable of stimulating proliferative and functional activity of main cellular elements of the tissue culture, of reducing spontaneous cell death rate, of enhancing regenerative-adaptive processes in proliferating and differentiating cells. It exerts trophic and stabilizing effects on morphological integrity and tissue regeneration of the liver, thus improving its functions.
Pre-clinical evaluation of biological effects of Ovagen has demonstrated, that its administration not only improves certain parameters of cellular and tissue homeostasis in liver cells, but also normalizes the functions of the digestive system as a whole, which are disordered under the influence of stress, adverse environmental factors, development of age-related pathology.
The number of patients with chronic liver lesions keeps on growing, this problem being widespread essentially among people in their working age. The increase in disease occurrence largely relates to adverse social and environmental factors.
Clinical trials were conducted on 106 patients with chronic hepatitis and cancer patients subjected to chemotherapy treatment, including 60 men and 46 women aged from 35 to 68 years (Table 3). The duration of the disease ranged from 3 to10 years. Patients of the main group (68 persons) received 2 capsules of Ovagen 2 times a day during meals, for 20 days, in addition to the conventional treatment. The control group consisted of 38 patients with similar health problems, and they received only conventional remedies.
The majority of patients complained of pains in the right hypochondrium, general weakness and rapid fatigability, 73% of patients suffered dуspeptical disturbances. 53% of patients revealed hyperbilirubinemia, high alanine aminotransferase level, increased globulin fraction of blood protein, mainly due to IgM fraction, which points out certain activity of chronic inflammatory process.
Patients’ complaints were estimated subjectively in dynamics, as well as by clinical blood and urine examination, blood biochemistry and immunity tests (immunoglobulins identification by Mancini). Ultrasound liver examination was also performed.
The majority of patients reported the absence of weakness, good appetite and increased working capacity after treatment with Ovagen. The intensity of pain syndrome essentially decreased in 53% of cases.
Cancer patients noted subjectively the improvement of general state, as well as decreased weakness and intensity of dyspeptical disturbances.
In the evaluation of Ovagen effectiveness special attention was paid to the results of biochemical studies, characterizing such liver functions as aminotransferase activity, pigmentary and protein producing performance.
After the completion of Ovagen administration, the majority of patients showed stabilization of biochemical indices: levels of bilirubin and alanine aminotransferase (table 4). Peripheral blood immunoglobulins, being the essential criterion of inflammatory process, showed a decreased level of IgM after Ovagen treatment (Table 5).
Thus, obtained results of clinical trials evidence hepatoprotective properties of Ovagen and expediency of its application in the complex treatment of acute and chronic liver lesions, for cancer patients exposed to radio- and chemotherapy, as well as for the prevention of liver diseases and their complications.
For many years the peptide preparations were available only as medicines, in the form of injections. However some years ago Prof. Khavinson and the Russian St. Petersburg Institute of Bioregulation and Gerontology created dietary supplements that can also reduce peptide deficiency and restore peptide-protein cycle in cells. They can be divided into natural (Cytomaxes) and synthesized (Cytogens) russian peptide bioregulators.
Natural russian peptide bioregulators (Cytomaxes)
Natural russian peptide bioregulators is a group of peptides of less than 50 amino acids and with a molecular mass of less than 5 kDa, free from foreign DNA or protein substance, extracted from organs and tissues of young calves by a patented method of thorough filtering. 5 kDa is very little. The molecular mass of DNA fragments and proteinaceous infectious particles, the prions, are several times bigger than that. Therefore these natural russian peptide supplements are extremely clean products. They do not have any immunogenic or mutagenic properties.
Inside the gastrointestinal tract the natural russian peptide bioregulators break down into amino acids and di-, tri- and tetrapeptides that match the DNA in a complementary way and activate protein synthesis in the respective body system. Their performance is gentle and gradual. Their effect continues to grow even after finishing the supplementation course and lasts up to 4-6 months until the peptide-protein cycle is impaired again.
Synthesized peptide bioregulators (Cytogens)
The analysis of natural peptides was used to detect the most active peptide from a group, which was later replicated in a lab. Synthesized (Cytogens) peptide bioregulators supplement contains only one peptide molecule whereas natural one includes a group of molecules. Synthesized peptides have an immediate impact compared to natural peptides and have a faster, yet more short-lived effect (1.5-2 months). Such peptides are typically used to start the initial peptide deficiency treatment. However, it is advised to switch to natural (Cytomaxes) peptides as a follow-up course.
Both types of peptides are efficient, safe to use, have no side effects and are compatible among themselves and with other products. As for the choice between natural and synthesized russian peptides, it depends on a particular situation. However, in most cases synthesized peptides, if available, are administered prior to the use of natural peptides.
Buy russian natural peptide bioregulators online from official distributor in US.
Vita-Stream is the only official distributor of the russian natural peptide bioregulators in United States. Vita-Stream works directly with the manufacturer in Russia. We have all the peptide variations available, both of natural (Cytomaxes) peptide , and synthesized (Cytogens) bioregulators.
Ingredients (per 1 capsule): peptide AC-3 (leucine, glutamic acid, aspartic acid). Inactive ingredients: microcrystalline cellulose (E460), beetroot sugar, lactose, starch, Tween-80.
Contraindications: an individual tolerance of components, pregnancy, lactation
Recommendations for application: adult men 1-2 capsules. 1-2 times a day during meals.
Receiving duration: one month, repeat every 4-6 months.
INTRODUCTION TO SYNTHETIC PEPTIDES
The Saint Petersburg Institute of Bioregulation and Gerontology (SPIBG) of the North-Western Branch of the Russian Academy of Medical Sciences for years has been developing a special approach to a new class of peptide-based supplements. As a result of the analysis of the amino-acidic sequence of peptides extracted from organs and tissues, physiologically active short peptides have been developed and later defined as a class of cytogenes, also known as the synthesized short peptides. This class of dietary supplements is characterized by a faster action compared to extracts: the physiological effects become evident after 24 hours, the main processes related to regulating work and functionality of organs and systems are launched. It is therefore considered highly important to take these synthetic peptides in the earliest stage of biotherapy.
On the other hand, the extracted peptides, widely known as the cytomax class, or the natural peptides, perform in a more delicate and gradual manner due to their so called specific physiological environment: it includes amino acids and microelements typical for that type of tissue from which they have been extracted in terms of quantity and quality. As a consequence of discrepancy in performance and effects of the different classes of peptides (synthesized or natural), SPIBG recommends their step-wise use as more reasonable. For instance, in the first four weeks a course of synthetic peptides can be taken, followed by one to two months of biotherapy based on natural peptides.
Synthesized Peptides Combinations
• Digestive system: OVAGEN VESUGEN CRYSTAGEN
• Vascular system: VESUGEN CRYSTAGEN
• Central nervous system: PINEALON VESUGEN OVAGEN
• Respiratory system: CHONLUTEN CRYSTAGEN VESUGEN
• Immune system: CRYSTAGEN VESUGEN OVAGEN
• Locomotor apparatus: CARTALAX VESUGEN CRYSTAGEN
• Adverse factors (radio - and chemotherapy, long-term ionizing irradiation, psychoemotional stress): VESUGEN OVAGEN CHONLUTEN
Please note: You should always consult a primary care physician/health practitioner of choice when considering the use of any products for health purposes, especially when undergoing treatment for an existing condition.
Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Information on this site is provided for informational purposes only and is not meant to substitute for the advice provided by your own physician or healthcare professional. You should not use the information contained herein for diagnosing or treating a health problem or disease, or prescribing medication.
*The information on this website is for informational and educational purposes only. It is not an attempt by the writers or publisher to diagnose or prescribe, nor should it be construed to be such. The information is not intended to replace medical advice offered by physicians. Readers are hereby encouraged to consult with a licensed health care professional concerning the information presented, which has been received from sources deemed reliable, but no guarantees, expressed or implied, can be made regarding the accuracy of same. Therefore, readers are also encouraged to verify for themselves and to their own satisfaction the accuracy of all reports, recommendations, conclusions, comments, opinions, or anything else published herein before making any kind of decisions based upon what they have read. If you have a medical condition, please consult your medical practitioner. Vita Stream, INC will not be liable for any direct, indirect, consequential, special, exemplary, or other damages arising from the use or misuse of any products, materials or information published.
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Featured positive reviews:
This is an awesome product, it has helped me a lot with my liver and I hope that continues.